(Solution) 1110 Principles Of Chemistry I, Spring 2016 IV Pre-Laboratory Activity (Topic 2) . Reminder: You Will Turn In A Copy Of Your Pre-lab As Soon As You... | Snapessays.com


(Solution) 1110 Principles of Chemistry I, Spring 2016 IV Pre-Laboratory Activity (Topic 2) . Reminder: You will turn in a copy of your pre-lab as soon as you...


Q: The LD50 (lethal dose 50%) is the dose that has a 50% probability of causing death; a higher LD50 means the substance is less toxic. Typical units are milligrams per kilogram, which means that the lethal dose in milligrams is divided by the animal mass in kilograms.  The data set:#/8 rats Dose, g/kg 0 1 0 2 0 4 4 8 5 12 8 16 a. Assuming that a normal distribution of mortality versus the logarithm of the dose (i.e., a lognormal distribution) is appropriate, estimate the LD50.  (Note - All deaths occurred within 24 h of dosing so this portion of their data addressed only acute effects of the compound.)b. Discuss your level of confidence in the result and how you might modify a subsequent experiment to better estimate this LD50.

 


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