(Solution) - It is observed that as temperature is increased most protein -(2025 Original AI-Free Solution)

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Academic Level: Undergrad. (yrs 3-4)

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Pages: 5 Words: 1375

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It is observed that as temperature is increased, most protein molecules go from their de?ned, folded state into a random-coil, denatured state that exposes more hydrophobic surface area than is exposed in the folded state.
a. Given what you have learned so far about ?H and ?S, explain why this is reasonable.
b. Sometimes, however, proteins denature as temperature is decreased. How might this be explained?